Base editor
Base editor: Cas9 nickase (nCas9) fused to a deaminase, guided by sgRNA to target DNA; the deaminase converts C to U (cytosine base editor) in the single-stranded R-loop, giving a C•G to T•A edit without a double-strand break
A detailed scientific illustration: base editor: Cas9 nickase (nCas9) fused to a deaminase, guided by sgRNA to target DNA; the deaminase converts C to U (cytosine base editor) in the single-stranded R-loop, giving a C•G to T•A edit without a double-strand break. Free SVG download under CC BY 4.0 for papers, posters and slides.
Format: SVG (editable vector). License: CC BY 4.0. Courtesy: Sciicons. Free to download and copy, no sign-in needed.
Keywords: base editor, base editors, base editing, cas9 nickase, ncas9, deaminase, cytosine base editor, cbe, abe, adenine base editor, crispr, gene editing, sgrna, genome editing
